Acacia subsidiary receives patents for wireless physiological monitoring technology Acacia Research Company announced today a subsidiary has acquired 11 patents for wifi physiological monitoring technology. ‘Acacia is quickly becoming the first choice in technology licensing and we continue to grow our base of future revenues with the addition of new patent portfolios,’ concluded Mr canadian pharmacy . Ryan. This patented technology generally pertains to the wireless transmission of physiological data such as heart blood and rate pressure. This technology has applications such as for example monitoring of implantable products, as well as home healthcare and fitness systems.
Acceleration of cell cycle transition kinetic could make human blood stem cells better For the very first time, the research group of Prof. Claudia Waskow at the Carl Gustav Carus Faculty of Medicine at Dresden Technical University is now describing a fresh mechanism in which the amount of the G1 phase of the cell cycle has a dramatic effect on the fitness of human blood stem cells. In the scholarly study, the shortened G1 phase led to much improved continuous creation of mature bloodstream cells from stem cells over a prolonged period of time. It really is imaginable that the stem cell function can also be increased in our body later on by an acceleration of cell cycle transition kinetic. The task has now been published in the Journal of Experimental Medicine . The continuous way to obtain freshly generated blood cells is essential to sustain the function of our disease fighting capability over the whole amount of our life. Actually, de novo era of bloodstream cells turns into pivotal after infectious illnesses or high blood loss when newly generated mature bloodstream cells are required to ensure survival of the organism. In order to cope with such life-threatening triggers, our bone marrow possesses so-called blood-forming or hematopoietic stem cells, that have the capability to re-form all the bloodstream cells as required. This specific real estate of hematopoietic stem cells is also used in clinical bone marrow transplantation, in which diseased blood cells – for example leukemic cells – are replaced by healthy cells. Nevertheless, the limited quantity of donor stem cells which may be tolerated by the recipient continues to be an extremely high hurdle for the success of such a stem cell transplantation. That is why better understanding of the function of stem cells in your body is still of particular importance to become able to find solutions for this issue. On the other hand, it remained unknown if the length of individual cell division phases regulates the behavior of hematopoietic stem cells. Nicole Mende, the doctorate student in Prof. Waskow's analysis group who processed the project, used gene transfer technology to specifically shorten the transit time through the first G1 stage of the cell cycle of human being hematopoietic stem cells. Due to the shortened G1 cell cycle phase transition, bloodstream stem cells were better maintained after stress induction in vitro. However, most importantly, after transplantation into a very ideal mouse model that was previously generated by the same laboratory, the group from Dresden could show that the function of the treated stem cells was also considerably increased in the living organism. Interestingly, a similar manipulation of the cell cycle, which affects a later point in time in the G1 phase however, shows precisely opposite results and a fast loss of the stem cell function. These results show that a well balanced transit velocity through the first and late G1 phase can be an important regulator of hematopoietic stem cell function and it consequently makes an important contribution to the lifelong maintenance of blood formation. Further, alterations of G1 transition kinetics may be the basis for practical defects of hematopoietic stem cells from aged mice or elderly human beings.