The drug faces patent expiration in 2016. READ ON >> 6. Latuda Sunovion aggressively promoted Latuvia in 2014 for the drug’s newer indication to treat bipolar depression. The manufacturer spent $179.1 million on TV spots and print ads in both wellness publications and mainstream journals. The 2014 advertising campaign targeted younger females and featured young actresses enjoying normal life. This was the 1st time Latuda broke into the top 10 10 most advertised drugs since its FDA approval in 2010 2010. Continue Reading >> 7.Three sufferers in the enoxaparin group died from a hemorrhage, and one patient in each combined group died from a pulmonary embolism. No autopsies were performed in either group. Multivariate logistic regression identified the next variables as factors that were independently associated with increased mortality at day time 30: a medical diagnosis of active cancer , chronic pulmonary disease , several acute illnesses , and renal impairment .