No significant difference was noted in general survival based on the degree of resection . Twenty-eight % of sufferers had a number of complications: major hemorrhage , loss of a normal organ during surgery , renal injury , vascular injury , pulmonary damage , nerve resection , wound complications , nephrectomy , and other complications . Only 12 of 479 patients received local radiotherapy ; of these patients, 1 patient had stage 4S disease, 5 sufferers experienced stage 3 disease, and 6 sufferers acquired stage 4 disease.A number of these can be chemical substances of concern and carcinogenic. #4 Flame Retardants: PBDEs are chemicals utilized as flame retardants. While flame retardant items are all around us and have been promoted as security standards, we must acknowledge the collateral toxicity of the consumer safety. #5: BPA : BPA is definitely a chemical that is used for decades in the creation of plastic meals containers such as for example baby bottles, water bottles, cans and in some dental sealants. BPA can leach into liquids and meals as containers are heated or damaged.