In the event that you burn up more calories than you eat, then you can expect to lose weight. However the body can burn off fat as heat also, a process called thermogenesis. This process kicks in when you go out into the cold, for example, losing fat to keep you warm and working, Kellis said. IRX3 and IRX5 become get better at controllers of the thermogenesis procedure, ordering your body to store surplus energy in body fat cells rather than burning it off, the researchers found.But surprisingly, 1727 of those 2,788 sufferers, or 62 percent of those suffering from liver damage, experienced no formal documentation within their medical records that that they had cirrhosis. The results suggest cirrhosis may be underdiagnosed in a large segment of the populace, he added. Clinicians typically depend on liver biopsies to diagnose cirrhosis. However in the hepatitis C individuals studied, only 661 patients were diagnosed with cirrhosis through a liver biopsy. ‘Our outcomes suggest a fourfold higher prevalence of cirrhosis than can be indicated by biopsy by itself,’ says Gordon. Related StoriesStudy displays uncommon HER2 missense mutations do not spread breast cancer on the ownMeat-rich diet may boost kidney tumor riskCornell biomedical engineers develop 'super organic killer cells' to destroy cancer cells in lymph nodesThe researchers discovered highly likely signs of liver harm by calculating the patients' liver enzymes, platelet counts and age in a previously validated test called a FIB-4 rating.